Laboratory of Protein Engineering

About Laboratory
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ABOUT LABORATORY

Laboratory organized in November, 2003 on the basis of the Peptide scanning group existed since 1992.

Main directions
  • Antigenic and functional mapping of proteins; protein-protein interactions; synthetic vaccines and immunodiagnosticums.
  • Analysis of hepatitis C virus (HCV) proteins and their functional mapping.
  • Study of hepatitis C virus protein immunogenicity, design of synthetic anti-HCV vaccine constructs.
  • Direction till 2001: Structural-functional mapping of proteins composing cytochrome P450-containing monooxygenase systems.
  • Solid-phase peptide synthesis.
Methods
  1. Peptide solid-phase synthesis, including multiple parallel synthesis;
  2. Protein and peptide purification;
  3. Peptide scanning;
  4. Analytical biochemistry;
  5. Protein chemistry: conjugation, modification, and affinity binding studies;
  6. Antibody preparation;
  7. Immunoassays.

Phone: +7 (499) 246-33-75