|
Russian Journal | ISSN 0042-8809 |
| Voprosy Meditsinskoi Khimii | Biomedical Chemistry |
Issue:
Volume 49, issue 2
Title: LIPID PEROXIDATION IN THE HEART OF ADULT AND OLD
RATS DURING THE IMMOBILIZED STRESS
Authors: V.N. Shvets, V.V. Davydov
Address: State Medical University, 26 Mayakowsky av., Zaporozhye, 69035,
Ukraine.
Abstract:
Lipid peroxidation (LPO) in the heart of adult (10-12 month) and old (22-25 month)
Wistar male rats was investigated during immobilized stress. Immobilization of rats was
accompanied by increasing the concentration of all studied LPO intermediates in the
myocardium of both age groups. Accumulation of LPO products in old rat hearts was
considerably higher than in adult ones. Dimethyl sulfoxide injection limited
stress-induced stimulation of LPO. There were age related variations in efficiency of this
antioxidant effect on the heart during immobilized stress.
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