Authors: I.A.Chernova, A.A.Demin, L.K.Shataeva

Address: Institute of Macromolecular Compounds Russian Academy Sci., Bolshoi pr.31, St.-Petersburg, 199004 Russia; fax: (7-812)328-6869, e-mail: chernova@mail.macro.ru

Abstract:

Low-pressure ion-exchange chromatography was used for isolation of chorionic gonadotropin (hCG) from urine of pregnant women. The purified hCG-preparations from various blood group donors were shown to differ in their sialic acid content. The highly purified hCG-preparations after gel chromatography were analyzed in the reaction of hemagglutination and the preliminary results suggest their blood group specificity.

Key words: human chorionic gonadotropin (hCG), sialic acids, blood group specificity, ABO-polymorphism

[Back]