Authors:  V.N. Zinovjeva, A.A. Spasov

Address: Pharmacological Research Institute and Department of Pharmacology of Volgograd State Medical University, Pavshikh Bortsov Sq., 1, Volgograd, 400066 Russia

Abstract: Free radicals attack cell genome in oxidative stress conditions accompanying many human diseases. Mutagenic and carcinogenic xenobiotics cause oxidative DNA damages also. Oxidative DNA damages become intensive in aging organisms. The data on natural and synthetic antioxidants protecting DNA from oxidation are presented in this review.

Key words: oxidative DNA, damage, antioxidants, DNA protection.

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