Russian Journal
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Russian Journal |
ISSN 0042-8809 |
| Biomeditsinskaya Khimiya | Biomedical Chemistry |
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Issue:
Volume 50, issue 6
Title: INFLUENCE OF COMPLEX PLANT POLYPHENOL PREPARATION EKLIKIT ON PROCESS OF LIVER FUNCTIONS RECOVERY AFTER ALCOHOL INTOXICATION
Authors: N. F. Kushnerova1, V.G. Sprygin1, Yu. A. Rakhmanin2
Address:
1 V.I. Il'ichev Pacific Oceanological Institute Far Eastern Branch of Russian Academy of Sciences, 690041, Vladivostok, 43, Baltiiskaya St., tel./fax: (4232) 312-573
2 A.N. Sysin Research Institute of Human Ecology and Environmental Health, RAMS, 119833 Moscow, 10, Pogodinskaya str.
Abstract:
The comparative study was carried out to estimate hepatoprotective activity of the preparation "Eklikit", that represents the extract from the Shizandra ñhinensis crests and reference hepatoprpotector "Legalon" under acute alcohol intoxication. It was found that "Eklikit" posseses membrane protective and expressed hepatoprotective activity. "Eklikit" exceeds the reference hepatorpotector, "Legalon", in its ability to increase the oxidized form of NAD+ and reduced glutatione, cholesterol ethers and reduce the time of thiopental sleep. In other cases "Eklikit" was equally effective to "Legalon".
Key words: plant polyphenols, ethyl alcohol, hepatoprotectors, liver
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