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Issue:
Volume 51, issue 2

Title: ENZYMES OF PURINE NUCLIOTIDE METABOLISM IN ESTIMATION OF FUNCTIONAL VALUE OF IMMUNITY

Authors: S. O. Tapbergenov¹, T. S. Tapbergenov²

Address:
¹Semipalatinsk State Medical Academy, SSMA, Abaia st., 105, Semipalatinsk, 490050 Kazakhstan; e-mail: salavat@relcom.kz
²Pavlodar branch SSMA, Pavlodar, 637000, Kazakhstan; e-mail: tapberg@unicode.kz

Abstract:

Blood lymphocyte activities of 5`-nucleotidases, adenosine deaminase and AMP deaminase have been investigated for evaluation of immune system state of albino rats under normal conditions, immobilization stress and effect of radiation. Stress-induced reactions were characterized by changes of activities of these enzymes. However the rations of activities 5`-nucleotidase\AMP-deaminase (coefficient A) and adenosine-deaminase\AMP-deaminaze (coefficient B) were even more informative than separate analysis of these enzymes.

Key words: immune deficit, enzymes, adenosine deaminase, 5`-nucleotidase, AMP deaminase, stress, radiation

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