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Russian Journal

ISSN 0042-8809
Biomeditsinskaya Khimiya

Biomedical Chemistry


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Issue:
Volume 51, issue 6

Title:RESISTANCE FOR THERAPY OF HELICOBACTER PYLORI INFECTION. NEW POSSIBILITIES FOR PROBLEM SOLUTION USING THE MASS-SPECTROMETRY METHOD

Authors: N. V. Semenova, N. A. Shubina

Address:

V. N. Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Pogodinskaya, 10, Moscow, 119121 Russia; tel.: (495) 939-70-51; e-mail: choun@mail.ru

Abstract: The chromato-mass-spectrometric [13C] urease breathe test is a promising tool for quantitative analysis of abundance of bacteria Helicobacter pylori and resistance to the antibacterial therapy. It was shown that the control of bacteria eradication at the time intervals recommended by conventional protocol and the second line therapy allow excluding the repeated attacks of disease associated with Helicobacter pylori in 10% patients.

Key words: bacteria Helicobacter pylori, resistance, breath test


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