Russian Journal

ISSN 0042-8809

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Issue:
Volume 53, issue 2

Title: BIOCHEMICAL AND IMMUNOLOGICAL MARKERS OF INSUFFICIENCY OF BLOOD CIRCULATION AT CHILDREN WITH CARDIOMIOPATHIES

Authors: T.V. Bershova, J.V. Shmatkova, A.P. Ivanov, M.I. Bakanov, E.N. Basargina, R.B. Zurabova, S.V. Monaenkova, J.V. Gerasimova

Address: Children’s Health Research Centre of Russian Academy of Medical Sciences, Lomonosovsky Prospect 2\62, Moscow, 119261 Russia; tel.: (495) 134-03-41, 134-37-60

Abstract:

Complex clinical-laboratory investigation of children with congestive heart failure (CHF)       developed on the basis of dilated cardiomyopathy and hypertrophic cardiomyopathy has been carried out. The development of CHF in children with cardiomyopathy was accompanied by changes of blood serum lactate, MB isoform of creatine phosphokinase, TNF-α, interleukin-6 (IL-6) (but not IL-2), and soluble receptors for IL-2 and IL-6.

Key words: congestive heart failure, hypoxia, cardiomyopathies, cytokines, soluble receptors of cytokines, neopterin.

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