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Russian Journal

ISSN 0042-8809

Biomeditsinskaya Khimiya

Biomedical Chemistry


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Issue:
Volume 53, issue 6

Title:STUDY ON INTERACTION OF ACETALDEHYDE WITH THIOALCOHOLS BY INFRARED SPECTROSCOPY.

Authors: G.N. Bondarenko1, S.M. Zenovich2.

Address:

1. A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky Prospect, 29, Moscow, 119071 Russia;

2. Moscow Centre for Narcology, Lublinskaya Street, 37/1, Moscow, 109390 Russia; tel.: (495) 179-29-18; e-mail: s.zenovich@mail.ru

 Abstract:

The reaction of acetaldehyde with thioalcohols, Mesna (monothiol) and Unithiol (vicinal dithiol) was investigated by infrared spectroscopy. Unithiol was more active in the reaction of acetaldehyde fixation than Mesna. This property may explain high efficiency of peroral administration of Unithiol for treatment of postalcoholic intoxication (hangover).

Key words: acetaldehyde, thioalcohols, postalcohol intoxication (hangover condition).

 


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