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Russian Journal

 ISSN 0042-8809
Biomeditsinskaya Khimiya

Biomedical Chemistry

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Issue: Volume 55, issue 3

Title: VITAMIN B1: METABOLISM AND FUNCTIONS

Authors: A.F. Makarchikov1,2

Address:

1Grodno State Agricultural University, Tereshkova Street 28, Grodno, 230008 Belarus; tel.: (152)720575; fax: (0152)721365; e-mail: a_makarchikov@yahoo.com

2Institute of Pharmacology and Biochemistry, National Academy of Sciences of Belarus, BLK 50, Grodno, 230009 Belarus; tel.: (0152)436301; fax: (0152)434121

Abstract:


    The review highlights metabolism and biological functions of vitamin B1 (thiamine). Thiamine transport systems, enzymes of its biosynthesis and degradation in various organisms, as well as molecular basis of thiamine-dependent hereditary patologies are considered. A special emphasis is given to discuss the role of thiamine triphosphate and adenylated thiamine triphosphate, a new thiamine derivative recently discovered in living cells.

 

Biomedical Chemistry, 2009 Volume 55, Issue 3, p. 278-297.

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