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Russian Journal

 ISSN 0042-8809
Biomeditsinskaya Khimiya

Biomedical Chemistry

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Issue: Volume 55, issue 3

Title: THE EFFECT OF SEASONS ON HYDROLYTIC AND TRANSALKYLATING ACTIVITY OF PHOSPHOLIPASE D IN THE MEMBRANES OF RAT LIVER

Authors:  G.Sh. Mirzaeva, L.S. Klemesheva, G.M. Irgasheva, K.T. Almatov

Address:

Mirzo Ulugbek National University of Uzbekistan, Biologic-Soil Faculty, Department of Human and Animal Physiology, Universitetskaya ul., 1, Tashkent, 700174 Uzbekistan; tel.: (998712) 246-35-98

 Abstract:
    The seasonal effect on the hydrolytic and transalkylating activity of phospholipase D in the membranes of rat liver has been demonstrated. In summer the hydrolytic and transalkylating activity of the phospholipase D in rat liver mitochondria increased compared to the activity in winter. This implies that the rate of the formation of phospholipids in rat liver mitochondrial membranes is higher in summer. Perhaps, the revealed hydrolase-transferase reactions of phospholipase D are regular links in a single mechanism of seasonal compensatory-adapting responses of organisms.

Key words: liver, mitochondria, phospholipase D, phospholipids.

Biomedical Chemistry, 2009 Volume 55, Issue 3, p. 338-342.

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