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Issue: Volume 55, issue 4

Title: GLUTATHIONE SYSTEM. II. OTHER ENZYMES, THIOL-DISULPHIDE METABOLISM, INFLAMMATION AND IMMUNITY, FUNCTIONS

Authors: V.I. Kulinsky, L.S. Kolesnichenko

Address:
Departments of Biochemistry and Biononorganic and Bioorganic Chemistry, Irkutsk State Medical University, Irkutsk, Russia; tel.: (395)224-0826; e-mail: kulinsky@pp.irkutsk.ru

Abstract:

The great significance of glutathione as a redox regulator and the reducing carrier has been established. There is a clear necessity for subdivision of an independent mitochondrial glutathione subsystem. The data on a specificity of glutathione metabolism in different organs are accumulated. The significance of glutathione system for inflammation and immunity has been proved. The investigations of glutathione system for elucidation of pathogenesis of diseases and its diagnostics are used in medicine.

Key words: glutathione, metabolism, enzymes, thiol-disulphide, inflammation, immunity, functions.

Biomedical Chemistry, 2009 Volume 55, Issue 4, p. 365-379.

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