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Issue: Volume 57, issue 4

Title: MASS-SPECTROMETRIC INVESTIGATION OF DEGRADATION OF THE INHALATION ANESTHETIC SEVOFLURANE IN FLOW ANESTHESIA.

Authors: A.Yu. Elizarov¹, T.D. Ershov², A.I. Levshankov³

¹A.F. Ioffe Physico-Technical Institute RAS, ul. Politekhnicheskaya, 26, Saint-Petersburg, 194021 Russia; tel.: 8 950 013 14 54; fax: 8 812 5344118; e-mail: a.elizarov@mail.ioffe.ru;

²State Technical University, ul. Politekhnicheskaya., 29, Saint-Petersburg, 195251 Russia;

³Kirov Military Medicine Academy, ul. Lebedeva, 6, Saint-Petersburg, 194044 Russia.

Abstract:

     The highest concentration of the Sevoflurane degradation product in the gas mixture was 65 ppm. Biochemical analysis did not reveal any nephro- and hepatotoxic effect

Key words: mass-spectrometry, anesthesiology, low-flow anestesia, sevoflurane.

Biomedical Chemistry, 2011 Volume 57, Issue 4, p. 469-476.

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