Russian Journal

ISSN 0042-8809

Issue:
Volume 45, issue 4

Title: PHOSPHOLIPID CONTENT OF CANCEROUS LUNGS

Authors: B. S. Khyshiktuev, Yu. R. Agapova, 1. V. ZhilIN, V. N. Ivanov

Address:
Chita Medical Academy, Gorky St., 39a, Chita, 672090, Russia.

Abstract:

Phospholipid spectrum of lung tissue fragments was studied in the dependence on the presence of malignant cells located at different distance from the focus of affection. Elevation of sphingomyelin (SM) level and lowering of phosphatidylcholine (PC) was noted in all analyzed patterns in pulmonary tissue. Alteration of growth malignant fields with extensive necrosis zones predominated in the same simples. The accumulation of phosphatidylinositol (PI) fraction and phosphatidylglycerol (PGL) deficiency was found. A similar tendency was supplemented with lysophosphatidylcholine (LPC) maximum on line of the extensive growth. It might be the result of invasive characteristic manifestation by tumor cells.

Key words: lung tissue, lung cancer, phospholipids.

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