Russian Journal

ISSN 0042-8809

Issue:
Volume 45, issue 6

Title: THE USE OF ION SELECTIVE FIELD TRANSISTORS (ISFETS) WITH PHOTOCURABLE POLYURETHANE MEMBRANES IN NEPHROLOGY FOR DETERMINATION OF K⁺ CONCENTRATION (ACTIVITY)

Authors: N. Yu. Abramova, Yu. A. BorIsov, A. V. Bratov, P. V. Gavrilenkov, K. DomingueZ*. V. N. Spiridonov, and E. D. Suglobova

Address:
Pavlov State Medical University, St. Petersburg, Russia

*Centro Nacional de Microelectronica (CNM), Barcelona, Spain

Abstract:

The applicability is examined of ion selective field transistors with photocurable polyurethane membranes to control of the electrolytic composition of dialyzing solutions used in artificial kidney apparatus, and also of plasma in patient treated by chronic hemodialysis. The short- and long-time characteristics of the efficiency of K⁺-selective field transistors in continuous contact with solutions. Comparative testing of such transistors and other sensing systems is made. It is demonstrated that a sufficient reliability of measurements in the range of physiological concentrations in combination with low cost provide the possibility of using K⁺-selective field transistors for monitoring of the potassium concentration both in dialyzing solutions and plasma in patients on chronic hemodialysis treatment.

Key words: nephrology, hemodialysis, blood, potassium, ionometry, ISFET

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