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    (204 bytes) Russian Journal ISSN 0042-8809
Voprosy Meditsinskoi Khimii

Biomedical Chemistry

Issue:
Volume 47, issue 1

Title: ENERGY-DEPENDENT SELECTIVE INTRACELLULAR PROTEOLYSIS STRUCTURE, ACTIVE SITES AND SPECIFICITY OF ATP-DEPENDENT PROTEASES

Authors: T.V. Rotanova

Address: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP-7 Moscow, 117871 Russia

Abstract:   

The enzymatic systems of selective proteolysis serving for the maintenance of cell homeostasis and functioning in prokaryotic and eukaryotic cells are characterized. The data on structure, active sites and specificity towards protein targets are given.

Key words: selective proteolysis, ATP-dependent proteases, proteasome, prokaryotes, eukaryotes. 

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