Russian Journal

ISSN 0042-8809

Issue:
Volume 43, issue 2

Title:
INCLUSION OF BETA-CAROTENE IN VARIOUS COURSES OF CHEMOTHERAPY OF LYMPHOLEUCOSIS L1210.

Authors:
Khabibulina V.M., Yurchenko N.Ya., Korostelev S.A., Shashkina M.Ya., Sergeev A.V.

Address:
Cancer Research Center (Moscow). Kazan State University

Abstract:
Possibility of including of synthetic beta-carotene in variuos courses of chemotherapy of lympholeucosis of mice BDF1 was investigated. In experimental models cyclophosphan and platidiam (50, 100, 200 and 8 mg/kg b.w. respectively) was used as anticancer drugs. Beta-carotene (5, 10, 20, 50 mg/kg b.w.) was administrated to mice in different schemes. During experiments it was observed that beta-carotene does not effect the rapeutic action of cyclophosphan and platidiam during treatment of lympholeucosis L1210.

Key words:
beta-carotene, lympholeucosis, hemotherapy, experimental models.

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