Russian Journal

ISSN 0042-8809

Issue:
Volume 43, issue 3

Title:
EFFECT OF CHRYSOTILE-ASBESTOS AND ZEOLITES DUST ON GENERATION OF ACTIVE OXYGEN SPECIES BY ALVEOLAR MACROPHAGES AND GRANULOCYTES

Authors:
Gusev V.A., Lomonosova O.S., Velichkovsky B.T.

Address:
Institute of Occupational Health RAMS, Moscow, Russia

Abstract:
Different characteristics of the influence of dusts of chrysotile -asbestos, mordenite, erionite and klinoptilolite on the total generation of the active forms of oxygen by the alveolar macrophages and the generation of O₂- and H₂O₂ by the granulocytes give the possibility to connect some of thise characteristics with the peculiarity of biological action thise dusts. It is discovered the most strong activating properties has the dust of chrysotile - asbestos, and the most cytotoxic effect has the dust of klinoptilolite.

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