Russian Journal

ISSN 0042-8809

Issue:
Volume 43, issue 3

Title:
THE INFLUENCE OF LEAD ON THE METABOLISM OF VITAMIN B GROUP AT THE ALIMENTARY IRON DEFICIT IN RATS

Authors:
Khotimchenko S.A., Kodentsova V.M., Alekseeva I.A., Vlaskina S.G., Vrzhesinskaya O.A., Sokolnikov A.A., Kharitonchik L.A., Aleshko-Azhevskiy Yu.P., Shevyakova L.V.

Address:
Institute of Nutrition, Russian Academy of Medical Sciences. Ustinskii pr., 2/14, Moscow 109240, Russia

Abstract:
Experimentally induced lead poisoning especially under simultaneous iron deficit leads to the development of secondary thiamine insufficiency. Erythrocyte riboflavin content and erythrocyte glutathion reductase and aspartate aminotransferase activities have been demonstrated to be increased. Lead treatment is accompanied with the increase of urina ry excretion of riboflavin, 4-pyridoxic acid and 1-vtthylnicotinamide in rats fed with adequite diet. Thus lead intoxication and iron deficiency influence vitamin B group metabolism.

Key words:

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