Russian Journal

ISSN 0042-8809

Issue:
Volume 43, issue 5

Title:
THE DEVELOPMENT OF A NEW GENERATION OF VACCINES ON THE BASIS OF STRUCTURAL CONJUGATES OF ANTIGEN AND SYNTHETIC POLYMER IMMUNOMODULATORS

Authors:
R.M. Khaitov

Address:
State Research Centre - Institute of Immunology, Moscow

Abstract:
The immunogenetic principle of creation of artificial antigens and vaccines possessing the abnormal immunogenecity and having capability to induce the high immune response in weakly reacting individuals have been suggested and proved by experiment. The vaccines of a new generation against the grippe pathogene, salmonellosis have been developed on the basis of this principle. In theory the methods of receiving allergovaccines for allergy disease therapy have been worked out and based.

Key words: vaccine, antigen, synthetic polymer immonomodulators