Russian Journal

ISSN 0042-8809

Issue:
Volume 44, issue 4

Title:
ERYTHROCYTE ABILITIES TO DEPOSITE THE THYROID HORMONES : REGULATORY ROLE OF PHYSICO- CHEMICAL FACTORS IN VITRO

Authors:
Dolomatov S.I., Pishak V.P., Slipenyuk T.S., Meschishen I.F., Okopnaya T.V.

Address:
Bucovina State Medical Academy, Chernovtsy, 274000, Ukraine

Abstract:

Data obtained suggest the existence of regulation mechanism controlling parameters of thyroid status, that does not require any modification of thyroid gland secretory function. The realisation of this mechanism can involve hormone-depositing function of blood erythrocytes, which is sensitive to a) change of regionar or systemic pH and b) change of hematocrit. Results of the present study indicate that mammalian erythrocytes are able to bind considerable quantities of T₃ and T₄ and, T₃ binding is preferable.

Key words: T₃, T₄, erythrocyte, acid-basal equilibrium.

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