Russian Journal

ISSN 0042-8809

Issue:
Volume 45, issue 3

Title: The influence of Mexidol and Its Structural Components on carbohydrate Content and Lipid Peroxidation During Acute Stress

Authors: T. A. Devyatkina, R. V. Lutsenko, E. M. Vazhnichaya, L. D. Smirnov*

Address: Ukraine Medical Stomatological Academy, Poltava *All-Russian Research Centre on Safety of Biologically Active Compounds, Staraya Kupavna

Abstract:

The influence of mexidol (3-hydroxy-6-methyl-2-ethylpyridine succinate) and its structural components (3-hydroxy-6-methyl-2-ethylpyridine and sodium succinate) and pyridoxine hydrochloride on carbohydrate content and lipid peroxidation was studied in the mouse liver under conditions of stress. Under stress conditions mexidol and pyridoxine exerted positive effects on peroxidation processes; mexidol also normalised glycogen content in the liver.

Key words: 3-hydroxypyridines, succinate, stress, liver.

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